Lipids and Lipid Derivatives
Medchemexpress LLC Mait-203 (acetate) | 99.1% | 2577.90 | 1 MG
MAIT-203 acetate is a cyclopentyalanin-derived peptidomimetic that potently inhibits the interaction of adenomatous polyposis coli (APC) and Asef (RhoGEF4). It binds APC-ARM with a Ki value of 0.015 μM and a Kd value of 0.036 μΜ, significantly repressing the migration and invasion of colorectal cancer cells.
- Reduces Asef-APC interaction in a dose-dependent manner in HEK293T cells.
- Attenuates SW480 and HCT116 cell migration.
- Decreases the amount of active CDC42 in SW480 cells.
Medchemexpress LLC Macupatide acetate | 99.9% | 4984.60 | 1 MG
Macupatide acetate is a glucose-dependent insulinotropic polypeptide (GIP) receptor agonist that improves insulin secretion responses and insulin sensitivity. It can be used for the research of type 2 diabetes.
- GIP receptor agonist
- Improves insulin secretion responses
- Enhances insulin sensitivity
- Suitable for type 2 diabetes research
- Produces larger insulin sensitivity improvement compared to selective GLP-1 RA Dulaglutide
- Exhibits additive effects on insulin sensitivity when combined with other agents
Medchemexpress LLC Histrelin acetate | 220810-26-4 | 99.9% | 1323.50 (free base) | 10 MG
Histrelin acetate is a GnRH analogue and a GnRH Receptor agonist. It increases serum luteinising hormone (LH), follicle stimulating hormone (FSH), and testosterone levels. It can be used in the research of prostate cancer and endometriosis.
- Stimulates the release of vasopressin (VP) and oxytocin (OT) from isolated rat hypothalamo-neurohypophysial explants.
- Rescues circulating LH concentrations in Csfmop/Csfmop mice.
- Reduces the number of endometrial glands, atrophying the stroma in rabbits.
Medchemexpress LLC Glp-1(7-37) acetate | 1450806-98-0 | 99.59% | 3355.67 (free base) | 10 MG
GLP-1(7-37) acetate is an intestinal insulinotropic hormone that augments glucose induced insulin secretion and is for research use only.
- Augments glucose induced insulin secretion
- Solid appearance
- White to off-white color
- Sequence: His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Gr-Gly
- Soluble in H2O: 50 mg/mL (ultrasonic and adjust pH to 1 with HCl)
- Soluble in PBS: 2 mg/mL (clear solution; need ultrasonic)
Medchemexpress LLC Bradykinin acetate | 6846-03-3 | 99.6% | 1060.21 | 10 MG
Bradykinin acetate is a potent endothelium-dependent vasodilator known for its ability to lower blood pressure. It is involved in inducing contraction of bronchial and intestinal non-vascular smooth muscle, increasing vascular permeability, and participating in pain mechanisms. This compound is suitable for various research applications, including studies on its role in cardiovascular function, inflammation, and cellular signaling pathways.
- Effective endothelium-dependent vasodilator
- Lowers blood pressure
- Induces contraction of bronchial and intestinal non-vascular smooth muscle
- Increases vascular permeability
- Participates in pain mechanisms
- Stable for 2 years at -80°C as powder
- Stable for 6 months at -80°C in solvent under sealed, moisture-free conditions
Medchemexpress LLC Ulipristal acetate | 126784-99-4 | 475.62 | 100 MG
Ulipristal acetate (CDB-2914) is an orally active, selective progesterone receptor modulator (SPRM). It stimulates the autophagic response selectively in leiomyoma cells and has potential for treating benign gynecological conditions like uterine myoma.
- Orally active, selective progesterone receptor modulator
- Stimulates autophagy in leiomyoma cells
- Potential for treating benign gynecological conditions, such as uterine myoma
- Blocks activin A modulation of fibronectin and vascular endothelial growth factor A (VEGF-A) mRNA expression
- Possesses significant antiprogestational activity in vivo
- Decreases incidences of fibroadenomas and adenocarcinomas in the mammary gland
Medchemexpress LLC Flecainide acetate (R-818) | 54143-56-5 | 99.4% | 474.39 | 1 ML
Flecainide acetate (R-818) is a class 1C antiarrhythmic agent primarily used for managing supraventricular arrhythmia. It functions by blocking the Nav1.5 sodium channel in the heart, which results in the prolongation of the cardiac action potential. This product is for research use only.
- It is a class 1C antiarrhythmic agent.
- It is especially used for the management of supraventricular arrhythmia.
- It works by blocking the Nav1.5 sodium channel in the heart.
- It causes prolongation of the cardiac action potential.
Medchemexpress LLC PRT062607 acetate | 1370261-98-5 | C21H27N9O3 | 100 MG
PRT062607 acetate is a solid chemical identified for laboratory use and substance manufacturing. It is recommended to store this product at 4°C, sealed and away from moisture. When in solvent, store at -80°C for up to 6 months or -20°C for 1 month, also sealed and away from moisture. Shipping at room temperature is acceptable for periods less than 2 weeks.
- Identified for laboratory chemicals and manufacture of substances
- Stable under recommended storage conditions
- Recommended storage at 4°C, sealed, away from moisture
- Storage in solvent at -80°C for 6 months or -20°C for 1 month, sealed, away from moisture
- Appearance: Solid
Medchemexpress LLC Cggk acetate | 96.8% | 363.43 | 10 MG
CGGK acetate is a control peptide for CAQK peptide. This peptide is provided as a solid, white to off-white appearance with a purity of 96.78%. It is suitable for various research applications.
- For research use only
- Ships at room temperature in continental US
- Store sealed, away from moisture
- Soluble in DMSO (≥ 100 mg/mL)
Medchemexpress LLC α-Amyrin acetate | 863-76-3 | 1 MG
α-Amyrin acetate is a pentacyclic triterpenoid compound with oral activity. It inhibits cancer cell proliferation, induces apoptosis, and reduces blood glucose levels. This compound is used for research in cancer and metabolic diseases, such as breast cancer and diabetes.
- Inhibits proliferation and colony formation in MDA-MB-231 cells.
- Induces apoptosis and increases caspase-3 activity in MDA-MB-231 cells.
- Promotes cleavage of Poly polymerase, increases E-cadherin, and inhibits vimentin and phosphorylated extracellular signal-regulated activation in MDA-MB-231 cells.
- Reduces blood glucose levels in diabetic rats.
Medchemexpress LLC JMV 449 acetate | 141863-45-8 | 99.7% | 807.03 | 1 MG
JMV 449 acetate is a potent neurotensin receptor agonist. It exhibits an IC50 of 0.15 nM for inhibiting 125I-neurotensin binding to neonatal mouse brain and an EC50 of 1.9 nM in contracting the guinea-pig ileum. This product also demonstrates highly potent and long-lasting hypothermic and analgesic effects in mice.
- Potent neurotensin receptor agonist
- IC50 of 0.15 nM for inhibition of 125I-neurotensin binding
- EC50 of 1.9 nM in contracting guinea-pig ileum
- Highly potent and long-lasting hypothermic effects
- Highly potent and long-lasting analgesic effects in mice
- White to off-white solid appearance
- Soluble in H2O at 100 mg/mL (requires ultrasonic)
Medchemexpress LLC LSD (acetate) | 945245-76-1 | 98.0% | 1009.20 | 10 MG
LSD acetate is a peptide utilized in targeted therapy and diagnosis research for tumor lymphatics. It specifically recognizes the lymphatics of C8161 melanoma, without binding to normal tissue lymphatics or tumor blood vessels. When conjugated with a proapoptotic peptide, it can effectively reduce the number of tumor lymphatics.
- Recognizes C8161 melanoma lymphatics
- Does not bind to normal tissue lymphatics or tumor blood vessels
- Reduces tumor lymphatics when conjugated with proapoptotic peptides
- Suitable for targeted therapy research
- Suitable for diagnosis of tumor lymphatics
Medchemexpress LLC DALDA (acetate) | 99.8% | 671.79 | 10 MG
DALDA acetate is a potent and highly selective μ-opioid receptor agonist with a Kᵢ of 1.69 nM. It exhibits antinociceptive and respiratory effects. This compound carries a net positive charge (3+) at physiological pH, making it hydrophilic and more polar than morphine.
- Potent and highly selective μ-opioid receptor agonist
- Kᵢ of 1.69 nM
- Exhibits antinociceptive effects
- Exhibits respiratory effects
- Carries a net positive charge (3+) at physiological pH
- More polar than morphine
Medchemexpress LLC BIMAX1 (acetate) | 96.1% | 3542.03 (free base) | 10 MG
BIMAX1 acetate is a tool peptide used to investigate the interaction of RBBP4 with importin β1 and its effects on the nuclear import pathway. It can be employed to study RBBP4's role in regulating nuclear import efficiency and cellular senescence.
- Utilized for investigating RBBP4 and importin β1 interactions
- Helps study nuclear import efficiency
- Can be used to research cellular senescence
- Appears as a white to off-white solid
Medchemexpress LLC R5 peptide (acetate) | 99.0% | 2013.26 | 10 MG
R5 peptide (acetate) is a laboratory chemical intended for research use only and should be handled by qualified scientists in appropriately equipped facilities. It is a white to off-white solid with a molecular weight of 2013.26 and a high purity of 98.99%.
- High purity: 98.99%
- Molecular weight: 2013.26
- Stable under recommended storage conditions
- Requires sealed storage, away from moisture
- Powder storage: -80°C for 2 years, -20°C for 1 year
- In-solvent storage: -80°C for 6 months, -20°C for 1 month